University of Central Florida Undergraduate Research Journal - Analysis of the Pathomechanism and Treatment of Migraines Related to the Role of the Neuropeptide CGRP
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Considering all that has been analyzed in terms of migraines and the relation to CGRP in various studies that have been conducted, it is the author's recommendation that additional CGRP receptor antagonists that are able to decrease the release of CGRP are the most promising avenue, and thus should receive particular attention. This experiment can effectively be conducted through analysis of CGRP effects under typical conditions, analysis of known CGRP receptor antagonists, and analysis of new CGRP receptor antagonists, an area where current research is lacking. In an ideal situation, this experiment would be conducted on ex-vivo dura mater from an animal such as a mouse.

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